Melanie Cornpropst Selected Research

Plasma Kallikrein

1/2022	Population pharmacokinetic modeling and simulations of berotralstat for prophylactic treatment of attacks of hereditary angioedema.
6/2021	Long-term safety and effectiveness of berotralstat for hereditary angioedema: The open-label APeX-S study.
1/2021	Oral berotralstat for the prophylaxis of hereditary angioedema attacks in patients in Japan: A phase 3 randomized trial.
1/2021	Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial.
1/2018	Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.
1/2016	Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat.

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Melanie Cornpropst Research Topics

Disease

6	Hereditary Angioedemas 01/2022 - 01/2016
4	Angioedema 01/2022 - 01/2018
3	Infections 01/2016 - 03/2013
2	Abdominal Pain (Pain, Abdominal) 01/2021 - 01/2021
2	Diarrhea 01/2021 - 01/2021
1	Fever (Fevers) 01/2021
1	Back Pain (Backache) 01/2021
1	Nasopharyngitis 01/2021
1	Vomiting 01/2021
1	Cough 01/2021
1	Chronic Hepatitis C 03/2013
1	Liver Diseases (Liver Disease) 02/2012

Drug/Important Bio-Agent (IBA)

6	Plasma KallikreinIBA 01/2022 - 01/2016
5	berotralstatIBA 01/2022 - 01/2018
2	BradykininIBA 01/2022 - 01/2018
2	ledipasvirIBA 01/2016 - 01/2014
1	Kallikreins (Kallikrein)IBA 01/2018
1	acivicin (AT 125)IBA 01/2018
1	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 01/2018
1	avoralstatIBA 01/2016
1	NucleotidesIBA 03/2013
1	CaspasesIBA 02/2012

Therapy/Procedure

1	Therapeutics 01/2021
1	Oral Administration 01/2018